The Wipro Science Education Fellowship (SEF) has two major components. The first component is the Wipro SEF Classic, a four-year professional development for K-12 STEM teachers that seeks to improve their teaching and leadership skills and ultimately foster positive district transformation. Cohorts of K-12 teachers participate in a rolling, two-year professional development experience that improves instruction and creates a district corps of teacher leaders. Professional development for fellows is led by a university in partnership with local school districts. After completing the Wipro SEF Classic, universities work with the Fellows and District Science Coordinators during the Innovation Phase. This component uses the talents and energies of past participants in unique ways to support continued school district transformation through teacher leadership. The program was developed at the Center of Science and Mathematics in Context (COSMIC) at UMass Boston and is now in seven universities and ~35 partner school districts throughout the United States.